The author, on the basis of an analysis of the strengths and weaknesses of the existing literature as well as the relevant opportunities and threats, proposes future directions for career counseling with lesbian, gay male, bisexual male and female, and transgendered persons. Suggestions include efforts for theory development, empirical research, career assessment, counseling practice, and counselor education. Whereas Tyler (1978) criticized the vocational behavior literature for concentrating on middle-class men, Fitzgerald, Fassinger, and Betz (1995) asserted that the study of women’s career development was probably the most active and vibrant area of vocational psychology research and theory from the 1970s to the early 1990s. The past decade has witnessed another significant advance in this literature, namely attention to the vocational behavior of lesbian, gay male, and bisexual male and female (LGB) persons. This new development is a response to the historical ignorance regarding sexual orientation and the heterosexual assumptions in career theories and research. Whereas the other articles in this special issue on the future of career counseling take a broad perspective, I concentrate on cutting-edge developments regarding the impact of sexual orientation on vocational behavior.